| 8/28 | N | Northwest (9-3) | [2:6] | L | 13-37 | |
| 9/7 | H | Oakridge (ON) (2-6) | [3:0] | W | 66-0 | |
| 9/12 | A | Wyoming (8-3) | [4:14] | W | 21-20 | |
| 9/21 | H | Carroll (2-8) | [3:10] | W | 42-20 | |
| 9/27 | A | Bishop Fenwick (6-4) | [4:14] | W | 35-28 | |
| 10/5 | H | Chaminade-Julienne (6-5) | [5:18] | W | 31-10 | |
| 10/11 | A | Archbishop Alter (11-2) | [4:14] | L | 20-51 | |
| 10/18 | A | Roger Bacon (4-6) | [5:18] | W | 36-7 | |
| 10/25 | A | Purcell Marian (3-7) | [5:18] | W | 38-22 | |
| 11/2 | H | Badin (10-3) | [5:18] | W | 38-24 | |
| 11/9 | H | # Urbana (10-1) | [4:14] | W | 28-14 | |
| 11/15 | N | # Clinton-Massie (14-1) | [4:14] | L | 14-52 | |
| # - Ohio playoff game | ||||||