| 8/23 | A | Buckeye Local (0-10) | [5:19] | W | 42-6 | |
| 8/31 | A | Nelsonville-York (4-6) | [6:23] | W | 38-0 | |
| 9/7 | H | Union Local (3-7) | [5:19] | W | 39-7 | |
| 9/14 | A | St Clairsville (12-1) | [4:15] | L | 13-41 | |
| 9/21 | A | Harrison Central (4-6) | [4:15] | W | 55-26 | |
| 9/28 | A | East Liverpool (6-4) | [4:13] | W | 27-26 | |
| 10/5 | H | Indian Creek (8-3) | [4:13] | L | 0-22 | |
| 10/12 | A | Wheeling Central Catholic (WV) (9-1) | [7:0] | L | 7-43 | |
| 10/19 | H | Beaver Local (4-6) | [4:13] | W | 40-15 | |
| 10/26 | H | Bellaire (8-4) | [5:19] | W | 34-0 | |
| 11/3 | H | # Bellaire (8-4) | [5:19] | L | 7-14 | |
| # - Ohio playoff game | ||||||