| 8/18 | H | Central Crossing (4-7) | [II:7] | L | 14-21 | |
| 8/25 | A | East (8-3) | [IV:15] | L | 22-32 | |
| 9/1 | H | St Charles (5-6) | [II:7] | L | 8-41 | |
| 9/8 | A | Eastmoor Academy (5-5) | [IV:15] | L | 8-26 | |
| 9/15 | A | Marion-Franklin (6-5) | [IV:15] | L | 12-38 | |
| 9/22 | H | South (4-7) | [III:11] | W | 46-6 | |
| 9/29 | A | Briggs (7-4) | [II:7] | W | 18-12 | |
| 10/5 | H | Africentric Early College (7-4) | [V:19] | W | 34-6 | |
| 10/13 | H | West (1-9) | [II:7] | W | 48-6 | |
| 10/20 | A | Walnut Ridge (3-8) | [II:7] | W | 54-30 | |
| 10/27 | H | # Watkins Memorial (8-4) | [II:7] | L | 8-18 | |
| # - Ohio playoff game | ||||||