| 8/19 | A | Franklin (3-7) | [III:12] | W | 36-14 | |
| 8/26 | H | Madison (1-9) | [V:20] | W | 45-0 | |
| 9/2 | H | Clinton-Massie (7-6) | [IV:16] | W | 17-7 | |
| 9/9 | H | Edgewood (11-2) | [II:8] | L | 0-10 | |
| 9/16 | A | Mount Healthy (5-6) | [III:12] | W | 50-19 | |
| 9/23 | H | Chaminade Julienne (6-5) | [III:12] | W | 24-7 | |
| 9/30 | A | Archbishop McNicholas (7-6) | [IV:16] | L | 14-21 | |
| 10/7 | A | Archbishop Alter (6-6) | [IV:16] | W | 10-0 | |
| 10/14 | H | Badin (13-1) | [III:12] | L | 6-14 | |
| 10/21 | A | Archbishop Carroll (3-7) | [III:12] | W | 39-6 | |
| 10/28 | H | # Eaton (7-5) | [IV:16] | L | 28-31 | |
| # - Ohio playoff game | ||||||