| 8/28 | H | Walsh Jesuit (13-1) | [2:5] | W | 35-7 | |
| 9/3 | H | Boone County (KY) (5-6) | W | 56-0 | ||
| 9/10 | H | Western Hills (7-3) | [1:4] | W | 42-6 | |
| 9/17 | H | Highlands (KY) (14-1) | W | 35-14 | ||
| 9/24 | H | Indianapolis Arsenal Technical (IN) (2-7) | W | 56-0 | ||
| 10/1 | A | La Salle (5-5) | [1:4] | W | 28-10 | |
| 10/8 | H | Archbishop Moeller (6-5) | [1:4] | W | 28-18 | |
| 10/15 | A | St Xavier (10-1) | [1:4] | L | 13-30 | |
| 10/29 | A | Oak Hills (7-4) | [1:4] | W | 16-15 | |
| 11/6 | H | # Oak Hills (7-4) | [1:4] | W | 14-0 | |
| 11/13 | N | # Centerville (11-1) | [1:4] | W | 49-42 | |
| 11/20 | N | # Wayne (13-2) | [1:4] | L | 14-24 | |
| # - Ohio playoff game | ||||||