| 8/25 | H | Wheeling Central Catholic (WV) (9-1) | [5:0] | L | 0-24 | |
| 9/1 | A | Caldwell (5-5) | [5:19] | L | 17-34 | |
| 9/8 | H | Shenandoah (8-2) | [5:19] | L | 0-34 | |
| 9/15 | A | Barnesville (7-3) | [5:19] | L | 0-20 | |
| 9/22 | H | Bishop Rosecrans (3-7) | [6:23] | L | 14-22 | |
| 9/29 | A | Harrison Central (0-10) | [4:13] | W | 14-6 | |
| 10/6 | H | St John Central (5-5) | [6:23] | L | 7-31 | |
| 10/13 | A | Bridgeport (0-9) | [6:23] | W | 68-0 | |
| 10/20 | H | Beallsville (9-2) | [6:23] | L | 30-42 | |
| 10/27 | H | Fort Frye (9-2) | [5:19] | L | 13-36 |