| 8/18 | H | Tippecanoe (10-3) | [III:12] | W | 21-7 | |
| 8/25 | H | Miamisburg (8-4) | [I:2] | L | 10-14 | |
| 9/1 | A | Valley View (13-2) | [V:20] | L | 21-42 | |
| 9/8 | A | Ponitz Tech (0-10) | [IV:16] | W | 49-0 | |
| 9/15 | A | Archbishop Alter (12-4) | [IV:16] | L | 13-20 | |
| 9/22 | H | Edgewood (4-7) | [II:8] | W | 38-17 | |
| 9/29 | A | Franklin (2-8) | [III:12] | W | 31-0 | |
| 10/6 | H | Monroe (2-8) | [III:12] | W | 49-6 | |
| 10/13 | H | Oakwood (4-7) | [III:12] | W | 37-13 | |
| 10/20 | A | Ross (3-7) | [II:8] | W | 37-13 | |
| 10/27 | A | # Wilmington (8-3) | [III:12] | W | 48-0 | |
| 11/3 | A | # Badin (13-1) | [III:12] | L | 6-24 | |
| # - Ohio playoff game | ||||||