| 8/30 | H | Ridgewood (9-2) | [6:21] | L | 6-34 | |
| 9/6 | H | John Marshall (WV) (5-5) | [3:0] | L | 6-33 | |
| 9/12 | A | Shadyside (11-1) | [7:25] | L | 7-20 | |
| 9/19 | A | Edison (2-8) | [4:13] | L | 16-19 | |
| 9/27 | H | Buckeye Local (1-9) | [4:13] | W | 61-0 | |
| 10/4 | A | Catholic Central (6-4) | [7:23] | W | 29-28 | |
| 10/10 | A | St Clairsville (11-1) | [5:17] | L | 10-35 | |
| 10/18 | H | Bishop Ready (5-4) | [6:21] | W | 30-0 | |
| 10/25 | H | Union Local (4-6) | [5:17] | L | 14-21 | |
| 10/31 | A | Martins Ferry (9-2) | [5:17] | L | 7-28 |