| 8/29 | A | Woodward (4-6) | [3:10] | W | 42-6 | |
| 9/5 | H | Independence (4-6) | [3:9] | W | 55-18 | |
| 9/12 | A | Edgewood (2-8) | [2:6] | W | 42-7 | |
| 9/19 | A | Roger Bacon (4-6) | [5:18] | W | 21-14 | |
| 9/26 | A | Bishop Fenwick (6-4) | [4:14] | L | 7-42 | |
| 10/3 | H | Carroll (2-8) | [3:10] | W | 35-0 | |
| 10/10 | A | Archbishop Alter (14-1) | [4:14] | L | 20-56 | |
| 10/18 | H | Chaminade-Julienne (5-5) | [5:18] | W | 55-49 | |
| 10/24 | H | Purcell Marian (3-7) | [5:18] | W | 42-21 | |
| 10/31 | H | Archbishop McNicholas (10-2) | [4:14] | L | 9-37 | |
| 11/8 | A | # Shroder (9-2) | [5:18] | W | 23-13 | |
| 11/15 | N | # West Jefferson (8-5) | [5:18] | L | 20-21 | |
| # - Ohio playoff game | ||||||