| 8/27 | A | Nelsonville-York (9-3) | [5:19] | L | 7-27 | |
| 9/2 | H | Belpre (4-6) | [7:27] | W | 49-6 | |
| 9/9 | A | South Gallia (3-7) | [7:27] | W | 42-0 | |
| 9/16 | H | Waterford (11-2) | [7:27] | L | 14-28 | |
| 9/23 | A | Miller (7-3) | [7:27] | W | 34-14 | |
| 9/30 | H | Wahama (WV) (2-8) | [7:0] | W | 46-0 | |
| 10/7 | A | Southern (8-3) | [7:27] | W | 42-14 | |
| 10/14 | A | Eastern (4-6) | [7:27] | W | 34-0 | |
| 10/21 | H | Alexander (1-9) | [5:19] | W | 55-13 | |
| 10/28 | H | Federal Hocking (0-10) | [7:27] | W | 44-0 | |
| 11/5 | H | # Southern (8-3) | [7:27] | W | 21-6 | |
| 11/12 | N | # Waterford (11-2) | [7:27] | L | 0-22 | |
| # - Ohio playoff game | ||||||