| 8/31 | H | Nelsonville-York (4-6) | [6:21] | W | 40-0 | |
| 9/6 | A | Wahama (WV) (9-1) | [6:0] | W | 12-7 | |
| 9/13 | H | South Gallia (6-4) | [7:25] | W | 48-0 | |
| 9/20 | A | Meigs (7-3) | [4:14] | W | 16-0 | |
| 9/27 | H | Miller (2-8) | [7:25] | W | 55-0 | |
| 10/4 | A | Waterford (2-8) | [7:25] | W | 48-0 | |
| 10/11 | H | Eastern (2-8) | [7:25] | W | 60-12 | |
| 10/18 | A | Belpre (5-5) | [6:21] | W | 54-0 | |
| 10/25 | H | Southern (8-3) | [7:25] | W | 42-14 | |
| 11/1 | A | Federal Hocking (5-5) | [6:21] | W | 59-0 | |
| 11/9 | H | # Beallsville (6-5) | [7:25] | W | 61-0 | |
| 11/16 | N | # Catholic Central (9-3) | [7:25] | W | 27-22 | |
| 11/23 | N | # Shadyside (12-1) | [7:25] | W | 21-14 | |
| 11/30 | N | # Western Reserve (13-1) | [7:23] | W | 14-10 | |
| 12/7 | N | # Marion Local (15-0) | [7:26] | L | 0-33 | |
| # - Ohio playoff game | ||||||