| 8/18 | A | Archbishop Carroll (2-8) | [III:12] | L | 18-21 | |
| 8/25 | H | Centennial (2-8) | [III:11] | W | 36-22 | |
| 9/2 | A | Belmont (1-8) | [II:8] | W | 28-0 | |
| 9/8 | A | West (1-9) | [II:7] | W | 36-32 | |
| 9/15 | H | Walnut Ridge (3-8) | [II:7] | W | 46-22 | |
| 9/22 | A | Independence (5-6) | [II:7] | L | 6-46 | |
| 9/29 | H | Eastmoor Academy (5-5) | [IV:15] | L | 24-30 | |
| 10/5 | H | Briggs (7-4) | [II:7] | L | 0-13 | |
| 10/12 | A | Africentric Early College (7-4) | [V:19] | L | 12-18 | |
| 10/19 | H | Marion-Franklin (6-5) | [IV:15] | L | 0-6 | |
| 10/27 | A | # Bishop Watterson (14-2) | [III:11] | L | 0-45 | |
| # - Ohio playoff game | ||||||