| 8/24 | A | East Liverpool (6-4) | [4:13] | L | 7-14 | |
| 8/31 | H | Monroe Central (2-8) | [7:27] | W | 55-0 | |
| 9/7 | H | Magnolia (WV) (7-3) | [6:0] | W | 50-20 | |
| 9/14 | H | Meadowbrook (9-4) | [5:19] | W | 26-22 | |
| 9/21 | A | Shenandoah (5-5) | [6:23] | W | 28-6 | |
| 9/28 | A | River (5-6) | [7:27] | W | 43-16 | |
| 10/5 | A | Beallsville (1-9) | [7:27] | W | 48-7 | |
| 10/12 | H | Bellaire (8-4) | [5:19] | W | 35-10 | |
| 10/19 | A | Bridgeport (3-7) | [6:23] | W | 55-6 | |
| 10/26 | H | Wheeling Central Catholic (WV) (9-1) | [7:0] | L | 13-14 | |
| 11/2 | H | # Adena (7-3) | [6:23] | W | 34-6 | |
| 11/9 | N | # Paint Valley (11-1) | [6:23] | W | 40-6 | |
| 11/16 | N | # Fort Frye (12-1) | [6:23] | L | 6-18 | |
| # - Ohio playoff game | ||||||