| 8/18 | H | Wheelersburg (9-4) | [V:19] | W | 17-14 | |
| 8/26 | H | Jackson (10-2) | [III:11] | W | 35-14 | |
| 9/1 | H | Fairland (9-2) | [V:19] | W | 62-14 | |
| 9/9 | N | Cabell Midland (WV) (9-1) | [I] | L | 21-34 | |
| 9/15 | A | South Point (5-6) | [V:19] | W | 42-8 | |
| 9/22 | A | Chesapeake (3-7) | [V:19] | W | 48-7 | |
| 9/29 | H | Rock Hill (4-7) | [VI:23] | W | 42-0 | |
| 10/6 | A | Coal Grove (4-7) | [VI:23] | W | 54-12 | |
| 10/13 | A | Gallia Academy (9-3) | [IV:15] | W | 27-17 | |
| 10/20 | H | Portsmouth (6-6) | [V:19] | W | 21-6 | |
| 10/27 | H | # Worthington Christian (4-7) | [V:19] | W | 56-6 | |
| 11/3 | H | # Heath (9-3) | [V:19] | W | 37-28 | |
| 11/10 | N | # Harvest Prep (12-2) | [V:19] | L | 14-20 | |
| # - Ohio playoff game | ||||||