| 8/20 | A | Bishop Rosecrans (4-7) | [VII:27] | W | 22-20 | |
| 8/27 | H | Manchester (1-6) | [VII:28] | W | 40-8 | |
| 9/3 | A | Southeastern (0-7) | [VI:23] | W | 42-24 | |
| 9/3 | A | South Gallia (1-7) | [VII:27] | C* | cancelled | |
| 9/10 | H | Lewis County (Vanceburg) (KY) (2-8) | [IV] | C* | cancelled | |
| 9/17 | H | Hillcrest Academy (0-8) | [VII:28] | C* | cancelled | |
| 9/24 | H | Eastern (1-7) | [VII:28] | W | 30-6 | |
| 10/1 | A | Northwest (5-6) | [V:19] | L | 0-20 | |
| 10/8 | A | Symmes Valley (9-1) | [VI:23] | L | 0-34 | |
| 10/15 | H | Green (1-5) | [VII:28] | W | 44-8 | |
| 10/22 | H | Notre Dame (7-3) | [VII:28] | L | 20-50 | |
| 10/30 | A | # Riverside (9-4) | [VII:28] | L | 7-55 | |
| * - game does not count in OHSAA rankings | ||||||
| # - Ohio playoff game | ||||||