| 8/18 | A | Linden McKinley (3-6) | [III:11] | L | 0-45 | |
| 8/25 | H | East (10-2) | [IV:15] | C* | cancel | |
| 9/1 | A | Centennial (2-7) | [III:11] | L | 8-34 | |
| 9/8 | H | Independence (7-3) | [II:7] | L | 8-64 | |
| 9/15 | A | South (8-2) | [III:11] | L | 3-46 | |
| 9/23 | A | Eastmoor Academy (4-5) | [IV:15] | L | 0-43 | |
| 9/29 | A | Africentric Early College (2-7) | [V:19] | L | 16-56 | |
| 10/6 | H | Walnut Ridge (2-7) | [II:7] | L | 0-42 | |
| 10/13 | A | Marion-Franklin (6-4) | [IV:15] | L | 6-36 | |
| 10/20 | H | Briggs (5-4) | [II:7] | L | 0-56 | |
| * - game does not count in OHSAA rankings | ||||||