| 9/9 | A | Kellenberg Memorial (2-1) | L | 18-21 | ||
| 9/17 | A | Rush-Henrietta (0-1) | W | 47-28 | ||
| 9/23 | H | Cathedral Prep (PA) (8-2) | [III] | W | 28-26 | |
| 9/30 | A | Archbishop Hoban (OH) (14-2) | [II:5] | L | 15-42 | |
| 10/8 | A | Erie (PA) (1-9) | [I] | W | 43-7 | |
| 10/15 | H | St Joseph's Collegiate (6-2) | W | 22-0 | ||
| 10/22 | A | Canisius (4-5) | [II] | W | 36-13 | |
| 10/28 | A | McDowell (PA) (9-2) | [I] | L* | 28-42 | |
| * - game does not count in OHSAA rankings | ||||||