| 8/26 | H | Notre Dame (7-3) | [7:27] | W | 21-14 | |
| 9/2 | A | Frontier (1-9) | [7:27] | W | 27-6 | |
| 9/9 | A | Wahama (WV) (2-8) | [7:0] | W | 46-8 | |
| 9/16 | H | Miller (7-3) | [7:27] | W | 41-0 | |
| 9/23 | A | Belpre (4-6) | [7:27] | W | 34-18 | |
| 9/30 | H | Federal Hocking (0-10) | [7:27] | W | 45-14 | |
| 10/7 | H | Trimble (9-3) | [7:27] | L | 14-42 | |
| 10/14 | A | Waterford (11-2) | [7:27] | L | 7-37 | |
| 10/21 | H | South Gallia (3-7) | [7:27] | W | 52-14 | |
| 10/29 | A | Eastern (4-6) | [7:27] | W | 41-27 | |
| 11/5 | A | # Trimble (9-3) | [7:27] | L | 6-21 | |
| # - Ohio playoff game | ||||||