| 8/31 | N | Carroll (4-6) | [3:12] | W | 35-28 | |
| 9/6 | A | Dublin Jerome (9-3) | [1:2] | L | 14-45 | |
| 9/13 | H | Notre Dame-Cathedral Latin (3-7) | [3:9] | W | 36-21 | |
| 9/20 | H | Archbishop Alter (7-5) | [3:12] | W | 35-31 | |
| 9/27 | A | Bishop Fenwick (5-5) | [3:12] | W | 42-22 | |
| 10/4 | H | Bishop Watterson (7-3) | [3:11] | W | 20-16 | |
| 10/11 | A | Belmont (4-6) | [3:12] | W | 28-7 | |
| 10/18 | A | St Charles (4-6) | [2:8] | W | 26-14 | |
| 10/25 | H | Steubenville (6-4) | [3:9] | W | 30-18 | |
| 10/31 | A | Bishop Hartley (12-2) | [3:11] | L | 13-20 | |
| 11/8 | A | # Turpin (10-1) | [2:8] | W | 27-13 | |
| 11/15 | N | # Harrison (11-2) | [2:8] | L | 7-42 | |
| # - Ohio playoff game | ||||||