| 8/18 | H | Lafayette Jefferson (1-1) | W | 55-14 | ||
| 8/25 | A | Brownsburg (2-1) | L | 31-45 | ||
| 9/1 | H | Penn (2-1) | W | 35-6 | ||
| 9/9 | A | Indianapolis Bishop Chatard (10-0) | [IV] | L | 21-24 | |
| 9/15 | A | North Central (Indianapolis) (0-3) | W | 49-6 | ||
| 9/22 | A | Frederick Douglass (KY) (5-4) | [II] | W | 28-19 | |
| 9/29 | A | La Salle (OH) (4-7) | [II:8] | W | 39-26 | |
| 10/6 | A | Roncalli (0-3) | W | 42-0 | ||
| 10/13 | H | Center Grove (9-1) | [I] | L | 38-45 | |
| 10/20 | Open date | * | ||||
| 10/27 | H | North Central (Indianapolis) (0-3) | W* | 42-2 | ||
| * - game does not count in OHSAA rankings | ||||||