| 8/18 | H | Brebeuf Jesuit Preparatory (0-1) | W | 27-17 | ||
| 8/25 | A | Lawrence Central (1-0) | L | 16-24 | ||
| 9/1 | H | Roncalli (1-1) | L | 7-21 | ||
| 9/8 | N | Indianapolis Cathedral (5-5) | [2:0] | L | 13-34 | |
| 9/15 | N | St Francis DeSales (OH) (6-4) | [3:11] | W | 42-7 | |
| 9/22 | A | Guerin Catholic (0-1) | W | 35-7 | ||
| 9/29 | H | Winton Woods (OH) (13-2) | [2:8] | L | 27-28 | |
| 10/6 | A | Covington Catholic (KY) (10-0) | [2:0] | L | 7-30 | |
| 10/13 | H | East Central (7-3) | [2:0] | W | 31-14 | |
| 10/20 | A | Indianapolis Northwest (0-1) | W | 62-6 |