| 8/21 | A | Gilmour Academy (7-3) | [IV:13] | L | 6-28 | |
| 8/27 | A | Westlake (4-5) | [II:6] | W | 30-7 | |
| 9/4 | A | Kenmore-Garfield (5-5) | [II:5] | W | 30-8 | |
| 9/10 | H | John Hay (4-7) | [II:5] | W | 36-0 | |
| 9/17 | A | John F Kennedy (2-7) | [III:10] | C* | cancelled | |
| 9/24 | A | Glenville (9-4) | [IV:13] | L | 0-22 | |
| 10/1 | A | Lutheran East (5-6) | [V:17] | W | 26-16 | |
| 10/12 | H | John Marshall (4-4) | [II:5] | C* | cancelled | |
| 10/15 | H | Lincoln West (0-6) | [III:10] | W | 60-0 | |
| 10/22 | H | East Technical (2-5) | [III:10] | W | 48-0 | |
| 10/29 | A | # Anthony Wayne (9-3) | [II:6] | L | 0-34 | |
| * - game does not count in OHSAA rankings | ||||||
| # - Ohio playoff game | ||||||