| 8/27 | H | Loudonville (OH) (1-9) | [VI:23] | W | 7-6 | |
| 9/4 | H | Slippery Rock (6-1) | [IV] | L | 10-35 | |
| 9/10 | H | Greenville (7-3) | [V] | W | 33-7 | |
| 9/17 | A | Jefferson Area (OH) (4-6) | [V:17] | W | 28-21 | |
| 9/17 | A | Lakeview (2-2) | C* | cancelled | ||
| 9/24 | H | Farrell (4-0) | L | 0-40 | ||
| 10/1 | H | Wilmington (6-2) | [VI] | L | 27-28 | |
| 10/9 | A | Kennedy Catholic (0-5) | W | 34-6 | ||
| 10/16 | A | Mercer (0-5) | W | 46-0 | ||
| 10/22 | A | Reynolds (5-4) | [VI] | W | 21-7 | |
| 10/30 | A | Mercyhurst Prep (3-5) | [IV] | W* | 63-13 | |
| * - game does not count in OHSAA rankings | ||||||