| 8/25 | H | St Edward (OH) (10-2) | [1:1] | L | 10-40 | |
| 9/2 | A | St Francis (NY) (4-5) | [3:0] | W | 23-21 | |
| 9/8 | H | Cathedral Prep (10-0) | [2:0] | L | 7-63 | |
| 9/15 | H | Football North (via Clarkson SS) (ON) (4-6) | [2:0] | L | 28-35 | |
| 9/22 | H | Fort LeBoeuf (2-4) | W | 42-13 | ||
| 9/29 | H | Hollidaysburg (0-1) | W | 42-38 | ||
| 10/6 | H | Erie (9-2) | [1:0] | W | 30-22 | |
| 10/13 | A | Austintown-Fitch (OH) (6-4) | [1:1] | L | 0-20 | |
| 10/20 | A | General McLane (0-3) | W | 37-20 | ||
| 10/28 | A | St Joseph's Collegiate (NY) (5-4) | [2:0] | L | 40-46 | |
| 11/3 | N | Erie (9-2) | [1:0] | L* | 34-35 | |
| * - game does not count in OHSAA rankings | ||||||