| 8/25 | A | Pickerington North (OH) (11-2) | [I:3] | L | 14-35 | |
| 9/1 | H | Kiski Area (0-1) | W | 48-0 | ||
| 9/8 | H | Penn Hills (1-1) | L | 20-26 | ||
| 9/15 | A | Seneca Valley (0-2) | W | 35-13 | ||
| 9/22 | H | Fox Chapel (0-1) | W | 50-0 | ||
| 9/29 | A | North Allegheny (3-1) | L | 10-45 | ||
| 10/6 | H | Central Catholic (9-1) | [II] | W | 26-19 | |
| 10/13 | H | Shaler (0-1) | W | 38-14 | ||
| 10/20 | A | Woodland Hills (0-2) | W | 28-0 | ||
| 10/27 | A | North Hills (0-1) | W* | 43-0 | ||
| * - game does not count in OHSAA rankings | ||||||