| 8/19 | H | Owensboro (0-1) | W | 28-14 | ||
| 8/26 | H | Central (Louisville) (0-2) | W | 44-8 | ||
| 9/2 | A | Male (Louisville) (2-2) | W | 24-10 | ||
| 9/16 | A | Elder (OH) (10-3) | [I:4] | L | 13-24 | |
| 9/23 | N | Trinity (Louisville) (6-4) | [I] | W | 13-8 | |
| 9/30 | H | Ryle (Union) (1-2) | W | 37-0 | ||
| 10/7 | H | DuPont Manual (8-2) | [II] | W | 21-10 | |
| 10/14 | A | Butler (Louisville) (0-2) | W | 38-6 | ||
| 10/21 | H | Pleasure Ridge Park (0-2) | W | 50-14 | ||
| 10/28 | H | Bowling Green (0-1) | W* | 31-0 | ||
| * - game does not count in OHSAA rankings | ||||||