| 8/19 | H | Gallia Academy (9-3) | [IV:15] | L | 7-44 | |
| 8/26 | A | Belpre (0-9) | [VI:23] | W | 50-0 | |
| 9/2 | A | Coal Grove (8-5) | [VI:23] | L | 34-61 | |
| 9/9 | A | Vinton County (6-5) | [IV:15] | L | 6-42 | |
| 9/16 | H | River Valley (3-7) | [V:19] | W | 37-20 | |
| 9/23 | A | Nelsonville-York (11-2) | [VI:23] | L | 0-35 | |
| 9/30 | H | Athens (2-8) | [III:11] | W | 48-22 | |
| 10/7 | H | Marietta (2-8) | [III:11] | W | 29-27 | |
| 10/14 | H | Wellston (0-10) | [V:19] | W | 40-0 | |
| 10/21 | A | Alexander (5-5) | [V:19] | W | 34-13 | |
| 10/28 | A | # Harvest Prep (13-1) | [V:19] | L | 0-47 | |
| # - Ohio playoff game | ||||||